Puberty Suppression - Medicine or Malpractice?

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The purpose of this document is to collect the highest-quality studies on puberty-blocking drugs and present their findings. This document’s primary research questions are:

  1. What are the effects of puberty-blocking drugs on the developing body?
  2. What are the effects of puberty-blocking drugs on mental health?
  3. To what degree, if any, are these effects reversible?

Substantial evidence from peer-reviewed scientific studies, case studies, and clinical trials suggests that puberty-blocking drugs can negatively affect the skeleton, cardiovascular system, thyroid, brain, genitals, reproductive system, digestive system, urinary tract, muscles, eyes, and immune system. Particularly urgent concerns for adolescents treated with puberty-blocking drugs are loss of bone mineral density and increased risk of osteoporosis; potential for decreased IQ and other cognitive deficits; increased risk of depression and suicidal thoughts; and stunted sexual and reproductive development. Evidence suggests that many of these effects are wholly or partially irreversible


bone healthcognitive impactsmental healthpuberty blockers